[1] Krikor (Grigore) Pambuccian was born in Adana, a city in the eastern Ottoman Empire (present Turkey).
During the Armenian genocide his family was forced to leave and ended up as stateless refugees, holders of the Nansen passport, going through Damascus, Cairo, Alexandria, Larnaca, to settle in Constanța.
There he studied at the Deutsche Evangelische Volksschule and at the Mircea cel Bătrân High School, which he graduated as Valedictorian.
Later on, the range of research topics widened to include the pathology of the heart and the blood vessels, the tumors of the heart, the pathology of the digestive tract, of the liver and the pancreas, the pathology of the infant, pre-cancerous states and in situ cancer, the pathology of the mouth (in particular Lichen planus), accidental and professional exposure to toxins (in the late 1960s and early 1970s doing an in-depth study of the toxic (carcinogenic) nature of the environment of Copşa Mică), toxic reactions to phenylhydrazine, hypertoxic forms of viral disease, suppurating pulmonary infections, cerebrotendineous xanthomatosis, visceral lesions in rheumatic disorder and rheumatoid arthritis, trichinosis, the reactions of the gastric mucosa to aspirin, and to aspirin combined with prednisone, experimental research in syphilis and in trichinosis, sudden infant death syndrome, and on hypertrophic cardiomyopathy caused by hypersecretion of adrenocortical hormones.
He pioneered the pathological study of the effects of dental implants on the oral cavity, in collaboration with Dr. Grigore Osipov-Sinești (1907-1989) and with Ernst Helmut Pruin (1913-2008) and Benedict Heinrich.