Durham was born in Rome, Georgia and was a stand-out wide receiver for the Calhoun High School Yellow Jackets football team.
[1] In his senior year, Durham helped lead the Yellow Jackets to a 14–1 record and an appearance in the state championship under coach Hal Lamb.
[7] While participating in spring practice in 2009, Durham tore the labrum in his left shoulder and it was later announced that he would miss the entire 2009 season.
[18] Durham signed with the Detroit Lions practice squad on September 2, 2012,[19] and was elevated to the active roster on December 4,[20] joining his former college roommate,[21] quarterback Matthew Stafford.
Durham recorded his first NFL touchdown catch in the Lions' final game of the 2012 season on December 30, on a 25-yard pass from Stafford.
The Panthers lost in the league playoffs semi finals in both seasons, failing to reach the Italian Bowl Championship game.