[3][4] After a theater internship in Florida,[3] Anderson-Lopez spent several years working temporary jobs while pursuing her dream of becoming a Broadway theatre performer in New York City.

[4] In 1999, she entered the BMI Lehman Engel Musical Theatre Workshop[2] and found her true calling as a lyricist, and also met her future husband Robert Lopez.

[5] In October 2003,[6] Anderson married Lopez, who would go on to become an EGOT-winning[7][8] songwriter, composer and lyricist, including three Tony Awards[9][10] for Avenue Q and The Book of Mormon.

[17] Her work for young audiences includes numerous short and full-length musical adaptations for Theatreworks USA (Diary of a Worm, Fancy Nancy, Condensed Classics).

Anderson-Lopez worked with her husband on the Disney Theatrical Productions stage musical adaptation of Frozen, with Jennifer Lee writing the book.

[18] Anderson-Lopez's first collaborations with her husband involved writing several songs together for children's televisions shows, such as Wonder Pets on Nick Jr. and Bear in the Big Blue House on the Disney Channel.

[27] Anderson-Lopez and Robert Lopez again collaborated in writing songs and lyrics for the 2017 Pixar film Coco,[28] for which she won for an Annie Award for Music in a Feature Production.