Pandya made his first-class debut on October 6, 2016, playing for Baroda during the 2016–17 Ranji Trophy tournament.

[7] He was selected to play for the Warwickshire County Cricket Club in the 2022 Royal London One-Day Cup.

He made his IPL debut in April 2016, playing against Gujarat Lions at Wankhede Stadium, Mumbai.

[9][10] In 2017, he scored 86 from 37 balls and took the wickets of Quinton De Kock and Zaheer Khan and was adjudged to be the Player of the Match against Delhi Daredevils at ACA-VDCA Stadium, Visakhapatnam.

[12] He had scored 160 against Railways in Ranji trophy with 21 boundaries and he was the highest run scorer in the first innings for Baroda with a strike rate of 73.06 in his second first class game.

[13] Later in the tournament, Pandya grabbed the attention over his questionable behavior again after being caught throwing moisturizer bottle towards Anukul Roy during the match against Rajasthan Royals.

[16] He made his T20I debut for India against the West Indies on 4 November 2018, taking one wicket and scoring an unbeaten 21 runs off 9 balls.

[23][24][25] In January 2021, Indian cricketer Deepak Hooda wrote a scathing letter addressed to the Baroda Cricket Association accusing Krunal Pandya of using ‘abusive language’ and ‘threats to end his career’ and Hooda pulled himself out of the Syed Mushtaq Ali Trophy 2021.

[27][28] In January 2022, Pandya's Twitter account was hacked, and suspicious tweets were posted from an alleged bitcoin scammer.