It flows through North Waziristan, and the city of Bannu, before joining the Indus River near Isa Khel.

It drains the southern flanks of the Spin Ghar mountain range and is a right-bank tributary of the Indus.

Kurram River mainly passes through the southern Tribal Areas of Khyber Pakhtunkhwa.

[2][3] The nearby Kurran-Garhi Project, finished in 1962, provides flood control and is used for irrigation and power.

Moreover, there exist a number of irrigation canals and civil channels on overtaking from the river.