The series stars Madhumita Sarkar, Rishi Kaushik and Aparajita Ghosh Das[5] in lead roles, the latter two for the third time since their corresponding portrayal of the characters "Indra" and "Mohor" in the 2005 Zee Bangla television drama serial Ekdin Pratidin,[6] and their respective characterizations of "Ujaan" and "Hiya" in the 2008 Star Jalsha romantic drama series Ekhane Aakash Neel, which ended in 2010.

Imon Mukherjee is a kind-hearted, studious, and short-tempered young girl who pass higher secondary exam and aspires to be a doctor.

She lives with her father, a police officer, Jayanta Mukherjee in Sundarpur, a village in North Bengal.

She is supposed to go to Kolkata to study in a medical college and to achieve this Jayanta decides to take early retirement from his job.

On the other hand, Ranojoy Chatterjee aka Rono, a Kolkata-based IPS Officer decides to go to Jaisalmer on a vacation.

Iman comes to the police station and tries to rescue Jayanta, but Akhil's goons hold her at a gun point too.

To take necessary steps against Gogna and Akhil, Jayanta files a request for an IPS officer to be posted in Sundarpur to deal with those goons.

Iman also requests Jayanta to not take part in the operation, but he does not listen to her either, telling her that he will retire after arresting Gogna.

Ranajay gets emotionally attached to Iman, seeing her efforts to help his family members, despite their behaviour towards her and subsequently falls in love with her, but cannot confess.

During Durga Puja celebrations, Iman helps Ranajay's cousin, Koli, reunite with and marry her lover, Dipto.

Iman learns about her pregnancy, but is abducted by the supposedly-dead Krishnamoy, who seeks revenge from Ranajay, having misunderstood his relationship with Shruti.

After Iman (now a medical intern) treats Gogna and saves him, he repents for his past actions and decides to mend his ways.

He arranges for her bail, and decides to find out the true culprits as well as the people responsible for illegal trafficking of new born children from the hospital.

Roopkatha grows jealous and agitated over Iman's happy and peaceful life, which she herself yearns for, having no children of her own.

Krishnamoy too arrives, having been released from jail, to take his son Michhil back with him, leaving Ranajay heartbroken.

Iman plans a family trip during which Badshah suffers a heart attack and suddenly dies.

After Roopkatha is diagnosed with severe depression, Ranajay stands by her to help her recover as she begins to seek him as a loved one to fill in her loneliness.

Iman and other family members feel insecure due to Ranajay's growing proximity towards Roopkatha, and everyone suspect them of having an affair.

A mentally unstable Roopkatha assumes herself to be pregnant and believes it to be Rono's child, leading a heartbroken Iman to leave the house with Pekhom and working overtime to make ends meet.

Roopkatha struggles to accept the fact and is finally made to leave the Chatterjee house for her own betterment so that she can start her life afresh.

Five years later, Roopkatha, now a college professor, meets Iman, now a professional doctor, to invite her to her wedding with Ranajay.

Secretly, Roopkatha plans to reunite Iman and Ranajay by remarrying them on the day of her wedding and their 12th marriage anniversary.

Lastly, Roopkatha, taking the heartfelt apologies, blessings and good wishes from the Chatterjees, marries Alok, marking a new phase in her life, as the series ends on a joyous note.

Screenwriter Leena Gangopadhyay[10] who has previously written down the script for Bengali TV shows like ETV Bangla's long-running drama series Sonar Horin and another daily soap Binni Dhaner Khoi, Zee Bangla's partition-themed love saga Keya Patar Nouko, and Star Jalsha's serials Ishti Kutum and Jol Nupur; developed the central idea for Kusum Dola.

[3] She made the main female protagonist, tentatively named Shimul, a village girl who is bright in her studies and quite upfront by nature.

[11] Rishi Kaushik who had previously collaborated with Ganguly and Banerjee in their production Ishti Kutum,[12] was selected to portray the lead role of IPS Ranajay Chatterjee a.k.a.

[14] Actress Madhumita Sarkar, noted for her portrayal of Juni in medical romance-drama series Care Kori Na, and Pakhi and Khushi respectively in the romance saga Bojhena Se Bojhena; was cast to portray Shimul (later named Emon).