At the age of 21 (in 1913), together with Lie Biauw Kie, Tjia Tjiep Ling, Tan Tjiang Ling, Liem Thoan Tik, and Liem Tjhioe Kwie, he founded the first weekly published in Surabaya named Bok Tok.
The first editor of the paper had been a European for legal reasons so Kwee was the first Chinese to hold this position.
In 1918 he was sent to Europe on behalf of the business firm Hoo Tik Thay in order to help them with tobacco exports, although he continued to write for Sin Po.
He returned to the Dutch East Indies in 1923 but when he arrived at the Port of Tanjung Priok he was refused entry.
His early staff were Liem Koen Hian, Mr. Ko Kwat Tiong, Kwee Tek Hoaij, Kwee Thiam Tjing, Njonja Tjoa Hin Hoei, Njonja Lim Sam Tjiang and Miss Thung Tien.