It is highly contaminated in its passage through the cities of La Quiaca and Villazón, on its right and left margins, respectively.

Between these two cities, across the river, is the Horacio Guzmán International Bridge, which is the only step enabled between the Argentine province of Jujuy and the Potosí Department.

The Argentine National Gendarmerie, through the Environmental Patrol of the La Quiaca Squadron is dedicated to the river cleaning project.

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