It is located in La Matanza Partido and is part of the Greater Buenos Aires metro area.

The station, located on the 28 km (18 mi) marker along the Haedo—La Plata line, primarily served the wholesale market established nearby in 1901, and in 1909, the settlement's first homestead lots were sold.

[1] Most of the settlement's 1,500 early homeowners worked in the wholesale market, which was closely tied to the Liniers cattle market just north of La Tablada, and numerous meat packing plants opened in the town during the 1910s and 1920s.

[1] The city grew moderately yet steadily in subsequent decades, and became home to the third-largest business and industrial community in La Matanza Partido.

La Tablada was declared a city by the Provincial Legislature on November 11, 1993.