Lachiewicz–Sibley syndrome is a rare autosomal dominant disorder characterized by preauricular pits and renal disease.
This disease was first described in a Caucasian family of British and Irish descent that emigrated to Ohio in the 19th century before settling in Nebraska.
Many of the members of this family still live in Nebraska, although the relatives are now scattered throughout the country.
Persons with BOR syndrome also present with hearing loss, branchial fistulas or cysts, malformed ears, and lacrimal stenosis.
Other anomalies in BOR syndrome may include a long narrow face, a deep overbite, and facial paralysis.