Lactucin is a bitter substance that forms a white crystalline solid and belongs to the group of sesquiterpene lactones.

It is found in some varieties of lettuce and is an ingredient of lactucarium.

It has been shown to have analgesic and sedative properties[1] which are speculated to occur via modulation of the GABAA receptor.

[2] It has also shown some antimalarial effects.

This article about a ketone is a stub.