[2] They were the children of Edward Seymour, 1st Duke of Somerset, who from 1547 was the Lord Protector of England after the death of King Henry VIII and during the minority of Jane's first cousin, King Edward VI.
She was baptised 22 February 1541, her godmothers were Lady Mary (the King's daughter, at the time declared illegitimate but later to become queen) and Katherine Howard, the fifth wife of Henry VIII, and queen at the time.
Some sources say that Thomas Cromwell was her godfather, but this cannot be correct as he had been executed the year before.
She was the sole witness to the secret marriage of her brother Edward to Lady Katherine Grey (a potential heir to Queen Elizabeth I) in 1560.
The Seymour sisters tended to work together, with their most famous work being a collection of 103 Latin distichs, Hecatodistichon, for the tomb of Margaret of Valois, queen of Navarre and also an author, which was published in 1550.