Lady Lushington first appeared in Lloyd's Register (LR) in 1809 with a listing of her departure on a voyage to India for the EIC.

Homeward bound, she was at Saugor on 15 February 1810, reached St Helena on 24 June, and arrived back at the Downs on 5 September.

[2] She sailed from there on 5 July, together with William Pitt, Lord Forbes, Harleston, and other East Indiamen, and under convoy of HMS Emerald.

Homeward bound, she was at Saugor on 24 February 1814, reached Simon's Bay on 16 June and St Helena on 5 September, and arrived at the Downs on 16 November.

British ships were then free to sail to India or the Indian Ocean under a license from the EIC.

Her heavy stores, 700 bales of cotton, and other goods, were unloaded into hoys belonging to the EIC.

Homeward bound, she was at Tellicherry on 29 October, reached St Helena on 24 January 1819, and arrived back at the Downs on 28 March.

[2] There is no mention in Lloyd's List's SAD data of any voyages by Lady Lushington in 1820.

[12] On 7 January 1821 Lady Lushington, Scott, master, sailed for Madras and Calcutta.

As Lady Lushington sailed from Madras to Calcutta, she was driven ashore and wrecked on 10 August 1821, 30 nautical miles (56 km) north of the mouth of the Koringa River, near Vizakapatam.