Lake Tikshozero (Russian: Тикшеозеро, Тикшозеро, Finnish Tiiksjärvi) is a freshwater lake, located in Loukhsky District of the Republic of Karelia and in Kandalakshsky District of Murmansk Oblast in Russia.

The outflow of the lake of the Lopskaya, which flows north as two separate streams (the Pudos and the Vincha) into Lake Kovdozero and belongs to the drainage basin of the Kovda and of the White Sea.

The lake has a very sophisticated form, with a big number of islands.

Almost all of the lake area lies in the Republic of Karelia, and only a gulf which serves as the outflow of the Pudos River is located in Murmansk Oblast.

It includes areas in the north of Loukhsky District, mostly located southwest of the lake.