Lakefront Airport was damaged by hurricane-force winds and the storm surge of Hurricane Katrina in 2005, and a number of the hangars and outlying buildings were destroyed.

With the exterior of the main terminal fully restored, however, the classic Art Deco building was used as the headquarters of the fictional company Ferris Aircraft in the 2011 action hero film Green Lantern starring Ryan Reynolds and Blake Lively.

During World War II the airfield was used by the United States Army Air Forces and housed the Tropical Weather School in 1945.

[7] The aircraft, with Hornady at the controls flying in heavy fog, crashed into Lake Pontchartrain while on final approach to Lakefront Airport.

On January 23, 2010, a United States Navy Beechcraft T-34 Mentor trainer crashed into Lake Pontchartrain just over a mile from the approach end of the airport.

The aircraft was intending to land at Naval Air Station Joint Reserve Base New Orleans but diverted to Lakefront Airport due to weather.

It has three asphalt runways: In the year ending December 31, 2022 the airport had 78,080 aircraft operations, average 214 per day: 88% general aviation, 3% military, and 9% air taxi.