Between 1304 and 1306, Giotto decorated the interior walls of the chapel with a series of frescoes depicting scenes from the Life of Jesus.
The upper sections of the walls also include stories of Joachim and Anna, parents of the Virgin Mary.
Both the monastery and the chapel now form part of the Musei Civici di Padova.
In the painting, the body of the crucified Christ has been lowered from the cross and laid on the ground, surrounded by his grieving mother and disciples.
To the right, Nicodemus and Joseph of Arimathea wait to prepare the body to be laid in a tomb.