2DIG393098386ENSG00000143815ENSMUSG00000004880Q14739Q3U9G9NM_002296NM_194442NM_133815NP_002287NP_919424NP_598576Lamin-B receptor is a protein, and in humans, it is encoded by the LBR gene.

It may mediate the interaction between chromatin and lamin B. Mutations of this gene has been associated with autosomal recessive HEM/Greenberg skeletal dysplasia.

Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.

[7] There is evidence tying it to Greenberg dysplasia[8] and Pelger-Huet anomaly.

[10] LBR also interacts with long non-coding RNA XIST in mouse cells and potentially assist the spreading XIST across X chromosome in differentiating female embryonic stem cells,[11] but it might be redundant for correct XCI in vivo.