[1] Nothing is known of Lando's early life, but he must have become a member of clergy of the papal court in Rome, through the influence of his colleagues Ugolino and Rinaldo.
Lando's diocese in Reggio was part of the Kingdom of Sicily, ruled by Frederick II, Holy Roman Emperor.
In 1222 he was appointed a commission to make judgements on disputed elections in the dioceses of Calabria, along with Lucas, bishop of Cosenza.
Lando accompanied him and helped negotiate the Treaty of Jaffa between Frederick and the sultan of Egypt, al-Kamil, through which Jerusalem was returned to the Christians.
By this time Lando was concerned that "envious" people were trying to turn Frederick against him, and he was "very much afraid of losing the royal favour.
In 1239 he reported to Frederick that he had been appointed the new Latin patriarch of Jerusalem, although he never served there, possibly because pope Gregory was suspicious of Lando's reconciliation with the emperor.