Operated by Prince George's County Public Schools, it serves students of grades 9 to 12.

[3][4] Other places served include sections of the CDPs of Kettering,[5] Brock Hall,[6] Forestville,[7] and Westphalia.

[9] Largo High School is located next to Prince George's Community College.

[10] In August 2014, former English teacher Jon Everhart won a $350,000 jury award after accusing the school system of discriminating against him because he is Caucasian.

It was alleged in his lawsuit against the school board that former principal Angelique Simpson-Marcus forced him out of his job because of his race and faced years of racial harassment from her.