[2] Entrepreneur Sheldon G. Adelson and his partners Richard Katzeff, Irwin Chafetz, Ted Cutler, and Jordan Shapiro bought the Sands Hotel and Casino in 1989.

The Sands Hotel was unable to compete with newer resorts on the Las Vegas Strip and was demolished to make room for The Venetian.

[7] The 2008 financial crisis forced Adelson to invest $1 billion of his own capital to keep the Las Vegas Sands in business, much of which the company spent developing event spaces and high-end retail stores in their properties By 2011, the Las Vegas Sands Corp.'s main profits came from renting convention space.

[8] The company soon recognized new commercial opportunities in Asia, specifically in Macau, the only Special Administrative Region of China where gambling is legal.

Las Vegas Sands Corp., along with Wynn Resorts and Galaxy Entertainment Group,[9] was one of the first to be granted a casino operating concession.

Las Vegas Sands Corp.'s future Macau properties were largely in Cotai, a district of reclaimed land created through public works projects and designated for hotels and casinos.

Development plans proceeded in 2010 for Marina Bay Sands resort in Singapore, at $5.6 billion the most expensive hotel and casino ever built.

In September 2012, the Las Vegas Sands Corp. announced that Madrid had been chosen as destination for a casino resort project dubbed EuroVegas in an attempt to expand outside of Asia.

Las Vegas Sands has proposed building an integrated resort at the Nassau Coliseum site in Uniondale, New York.

[23] As of 2021, the Las Vegas Sands Corp. is headed by CEO Robert Glen Goldstein, and reported a 2020 annual revenue of $3.61 billion.

[24] According to OpenSecrets, Las Vegas Sands donated $52.9 million to Republican candidates as the largest single contributor to federal campaigns during the 2012 election cycle.

[27][28][29] Adelson has also provided financial supporter to the Zionist Organization of America, the Yad Vashem Holocaust museum and memorial in Jerusalem, and multiple U.S. groups that fundraise for the Israeli military.

In March 2013, the New York Times[35] reported that the Las Vegas Sands Corp. had informed the U.S. Securities and Exchange Commission that the company likely violated federal law against the bribery of foreign officials.

[44] Prior to the November 2022 elections, Las Vegas Sands conducted a petition drive in Florida, spending $49.5 million to amend the State's Constitution to expand casino gambling.