It was designed by architect Luis Perocier and built in 1924 for Dr. Enrique Lassise, a physician and "remembered good-samaritan" of the town of Sabana Grande and his wife Matilde Schettini, a schoolteacher.

Perocier learned from more renowned Czech architect Antonin Nechodoma, who himself settled in Puerto Rico eventually after studying with Frank Lloyd Wright under Louis Sullivan.

While most of Nechodoma's works in Puerto Rico are gone; La Quinta survives as "one of the few major examples of prairie-influenced structures in Puerto Rico and the only intact manor house of its kind in Sabana Grande.

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