At the start of her career, she took part in several TV talent shows, including The Voice Brasil, in which she was a semi-finalist under the stage name Mayara Prado.

Prado is known as one of the main names in the feminejo movement and for her musical approach, which mixes genres such as sertanejo, rock and reggae, as well as more positive lyrics.

[5] The singer then went on to record the live album Verdade (2019), which included a re-recording of Cobaia and new songs with the participation of Fernando & Sorocaba and Gabriel Diniz.

[6][2] In 2020, the complete edition of Livre was released, recorded at the Hopi Hari amusement park in São Paulo, with special appearances by Matheus & Kauan, Bruno & Marrone, Fernando Zor and the band Maneva, with songs such as "Viva Voz", "Beijo Amador", "Sua Mãe Tá Nessa", "Você Humilha" and "Suor da Sua Boca".

With songs such as "Primeiro Eu", “Zap” and “Terminou Com Calma”, it was her second work nominated for a Latin Grammy in the category of Best Sertaneja Music Album.

[10] The project led to a follow-up and subsequent tour in 2023 with the album Raiz Goiânia, with musical production by Prado and William Santos.

[11] Also in 2023, Prado released the album Ao Vivo em Brasília, produced by Ivan Miyazato, and comprising songs such as "Desandei", "Tanto Faz" and "Whisky Vagabund0".

[12] In 2024, Prado presented the album Transcende, recorded live at the Ginásio do Ibirapuera, with the participation of Zé Neto & Cristiano, Nando Reis, Simone Mendes and Cristinas, produced by Eduardo Pepato.

[14] She has also collaborated with artists from different musical segments, such as forró singer Xand Avião,[12] rapper Edi Rock[15] and pagode band Sorriso Maroto.