[20] In September 2011, Iain Cook of Aereogramme and The Unwinding Hours produced Blue Sky Archives' Triple A-Side EP.

[24] Mayberry has collaborated with artists such as Marshmello,[25] Death Cab For Cutie,[26] Bleachers, The National,[27] the lead singer of Paramore, Hayley Williams,[28] and The Cure's frontman, Robert Smith.

[34] She co-wrote the song with award-winning Canadian songwriter Tobias Jesso Jr.[13] This was followed by the singles "Shame", "Change Shapes",[35] "Something in the Air"[36] and "Crocodile Tears" over the next year.

[37] Her ongoing work with the organisation includes written contributions to the online magazine and blog, and she can be heard regularly on TYCI podcasts.

[38] The group also holds live events, raising money for charities like Glasgow Women's Aid,[39] and produced a radio show.

[40] She wrote: "What I do not accept ... is that it is all right for people to make comments ranging from 'a bit sexist but generally harmless' to openly sexually aggressive.

"She discussed the issue again in a Talks at Google session in 2014[41] and on Channel 4 News, following aggressive responses to the band's video for "Leave a Trace".

[45] Mayberry is a patron of Rape Crisis Glasgow[9] and has been involved with other organisations such as WaterAid,[46] Yellow Bird Project,[47] Wild Aid[48] and Plus 1,[49] donating a portion of Chvrches' ticket sales to Amnesty International.

[52] In December 2016, Mayberry took part in a fundraiser show with Carly Rae Jepsen, Lorde and Charli XCX for the Ally Coalition,[53] an organisation started by Jack Antonoff to raise money for homeless LGBT youth.

[54] In 2018, Mayberry discussed the #MeToo movement during a BBC interview and explained how she was sceptical that much had changed:[32] "It's great that people are waking up and having that conversation, but it has to be more than a symbolic gesture," she says.

[55] Mayberry wrote on Instagram that "working with people who are predators and abusers enables, excuses and ultimately tacitly endorses that behaviour.

[17] Mayberry has been an outspoken critic of the Trump administration and has attributed his presidency with the rise of global activism for social issues, calling him "an unpunished sexual predator in office.

Following the Sutherland Springs church shooting, Mayberry released a video recounting her memory of the Dunblane massacre in which 16 children and one teacher were murdered with handguns, resulting in sweeping gun control legislation in the UK.

[60] Mayberry and actor Justin Long have engaged in multiple philanthropic activities together, including hosting a holiday variety show charity fundraiser at The Fonda Theatre in Los Angeles[61] and travelling together to Nicaragua to visit a women's shelter.