He is best known for hosting the Journal de 20 heures news bulletin and Un jour, un destin biographical show, both on France 2.

In 1999, he joined M6 as its chief editor and presenter of the newsmagazine De quel droit?

In September 2006, he joined France 2 where he replaced Carole Gaessler as fellow newspresenter David Pujadas' anchor on the 8pm newscast.

[1] Since January 2007, Delahousse has hosted his own show, Un jour, un destin [fr], a documentary series profiling key figures who have made a lasting impression on the public.

From February to June 2007, he also presented a weekly political show, Un dimanche de campagne.