[1] Prior to "Lay It All on Me", Rudimental had previously collaborated with Sheeran, co-writing the song "Bloodstream" which appeared on the latter's 2014 album, x.

[2] Writing the song, Rudimental's inspiration was evoked by the fact of being away from home and family.

[2] The official remix was released on 14 December 2015 featuring additional verses from Big Sean and Vic Mensa with a slightly different instrumental beat.

The song debuted on the UK Singles Chart at number 16, giving Rudimental their eighth top 40.

[3] The official music video was uploaded to Rudimental's YouTube channel on 6 November 2015.