In December 1988, the Department of Education and Training of Ba Ria-Vung Tau Province initiated a project for middle school for the gifted in two majors: Literature and Mathematics.

For the school year 1990-1991, the Chairman of the People's Committee of Vung Tau-Con Dao Special Administrative Region established Le Quy Don High School for the Gifted, with the campus located at 58 Tran Hung Dao Street, Ward 1, Vung Tau city.

After two years of construction, the new campus officially came into effect in November 2011, with better-equipped infrastructure and learning environment.

[3] In addition to studying, the school also provides an area for recreational and athletic activities including three outdoor basketball courts, a multi-purpose sports center, a football pitch, a swimming pool, an artificial lake, a theatre for performing arts activities, a park, and a 30-metre hill.

Students who want to be admitted must take an advanced written examination consisting of four tests: Mathematics, Literature, English, and a major subject exam.

The major subject exam is designed by the school committee with complicated questions both in research and practice fields to classify students into different classes based on their performances.

Approximately 350 students achieving the highest scores in the examination will be chosen from the competitive pool of thousands of candidates.

The school offers classes for these gifted students in the following majors: Mathematics, Physics, Chemistry, Biology, Vietnamese Literature, Information Technology, and English.