The town is located along the banks of the Arno river, at the point where the homonymous Sieci torrent flows (4 km), on the slopes of the Remole hillock (249 m).

The village of Sieci is mentioned in the thirteenth century for a place, called Lucente, located among the possessions of the archbishop's mess in Florence near San Martino a Sieci (today Molino del Piano).

In the early Middle Ages the castle of Remole acquired importance, which was confirmed in 1191 by the emperor Henry VI to the Benedictine nuns of Sant'Ellero, entrusting the patronage of the parish church of San Giovanni and its court to Guido Guerra, Count palatine of Tuscany.

Of particular interest are the parish church of San Giovanni, built in the Middle Ages in pure Romanesque style, and the now abandoned Brunelleschi pottery factory, the oldest in the area, dating back to 1774.

They represent one of the rare examples of an Italian industrial factory belonging to the late Middle Ages.