The school serves both communities of Le Sueur and Henderson, Minnesota for grades 6–12.

[5] The establishment that is now Le Sueur-Henderson Secondary School was founded in 1885.

[1] However, before its merger, the current establishment was simply named Le Sueur Secondary School.

Henderson High School had fully existed as an independent high school until 1986 when it had merged its athletics, Henderson Tigers, with nearby Arlington-Green Isle, Sibley East Bengals.

[7] State Champions: Le Sueur: 1982 Girls Golf, 1983 Girls Golf, 1986 Boys Basketball, 1989 Boys Golf, 2021 Softball Henderson: 1983 Girls Basketball Conference Affiliation: Minnesota River Conference 1959-2024 South Central Conference 2024–Present