The League of Catholic Women Building is located at 100 Parsons Street in Midtown Detroit, Michigan.

[2] As immigration was curtailed in the 1920s, the League shifted focus to assisting single young women who were seeking employment in the city.

The building also housed the League's offices, and included a cafeteria, a chapel, library, ballroom, auditorium and a rooftop garden.

[4] In the 1960s, the League began providing housing to women attending Wayne State University's School of Nursing.

[4] In 1994, the organization officially changed its name from the League of Catholic Women to Metro Matrix Human Services.