The Warren–Prentis Historic District is a historic district in Detroit, Michigan, including the east–west streets of Prentis, Forest, Hancock, and the south side of Warren, running from Woodward Avenue on the east to Third Avenue on the west.

[2] Due in part to the large lot sizes and the streetcar lines along Woodward and Third, the district became popular with upper-class Detroit businessmen and professionals moving away from downtown.

A number of these citizens moved into the area in the period between 1880 and 1895, commissioning residences.

[2] Commercial development in the area increased in the early 20th century, peaking in the years between World War I and the Great Depression.

[3] These homes were divided into rental units, and the area was fully utilized during the boom years of World War II.