She was captured in 1801 after she had delivered the captives she had gathered on her first voyage as a slave ship in the triangular trade in enslaved people.

Leander entered Lloyd's List (LR) in 1799 with Anderson, master, Huggins, owner, and trade London–Africa.

On 17 January 1801 a privateer of 22 guns and 160 men captured Leander, Anderson, master, as she was on her way from Jamaica back to London.

[4] French sources reported that the French privateer Mon Oncle Thomas, of Rochelle, fitted out by Citizen Segaray, had captured the British West Indiaman Leander, of 600 tons and twenty-six 18-pounder carronades, after an action in which the British captain was wounded.

[7] However, it was not always clear that a vessel lost on her way back to Britain from the West Indies was a Guineaman that had disembarked her captives.