4Q95922779235ENSG00000121207ENSMUSG00000028003O95237Q9JI60NM_001301645NM_004744NM_023624NP_001288574NP_004735NP_076113Lecithin retinol acyltransferase is an enzyme that in humans is encoded by the LRAT gene.

[5][6] Lecithin retinol acyltransferase is a microsomal enzyme that catalyzes the esterification of all-trans-retinol into all-trans-retinyl ester during phototransduction, an essential reaction for the retinoid cycle in visual system and vitamin A status in liver.

Mutations in this gene have been associated with early-onset severe retinal dystrophy.

[6] LRAT was overexpressed in colorectal cancer cells compared to normal colonic epithelium.

Strong LRAT expression was associated with a poor prognosis in patients with colorectal cancer.