According to the National Center for Education Statistics, in 2019, the school reported an enrollment of 298 pupils in grades 7th through 12th, with 3 pupils eligible for a federal free or reduced-price lunch.

[1] Leetonia High School offers courses in the traditional American curriculum.

Entering their third and fourth years, students can elect to attend the Columbiana County Career and Technical Center in Lisbon as either a part time student, taking core courses at LHS, while taking career or technical education at the career center, or as a full time student instead.

Students may choose to take training in automotives, construction technology, cosmetology, culinary arts, health sciences, information technology, multimedia, landscape & environmental design, precision machining, veterinary science, and welding.

[4] Elective courses can be in English, science, social studies, foreign language, technology and business, family and consumer science, and fine art.