Although acting and writing were her hobbies, her career ambition was to become a gynecologist, a plan that later changed when she developed an interest in forensics.

While studying criminology, another career change occurred when she met the Ghanaian actor Sam Odoi, who convinced her to write a script for him.

President of the Ghana Library Board Readers Club for three years, Djansi began her career in the entertainment industry in 1998 when she was a runner-up in a regional beauty pageant in junior high school.

Djansi followed with the advocacy film Sinking Sands which supports the Say No to Violence Against Women Campaign for UNiFEM Ghana.

Djansi's Like Cotton Twines was an official selection to the 2016 Los Angeles Film Festival under the World Fiction Section.

Her other credits include Where Children Play with Grammy winner Macy Gray, the LA Film Festival Best Episodic Television Show 40 and Single for AMC's Urban Movie Channel, and All The Men in my Life starring Rochelle Aytes.

She is also lauded for revolutionizing Ghana’s film industry with I Sing of Well, whichmarked the onset of a unique narrative style never before seen in West African storytelling.