The species is sexually dimorphic, with the males being considerably larger, and having red markings on the head around the lower jaw.

It mainly inhabits damp locations, but is also present in shaded parts of dry shrublands, including broadleaf woodland, pine forests, plantations, coastal scrub, gardens, arable land and pasture.

[1] This lizard was first recorded in Florida in 1994, where it was described as a newly arrived exotic species "likely to colonize natural areas".

[1] A study of anti-predator behaviour among these lizards showed that those that lived in more open, exposed locations, tended to display such traits as longer limbs and faster sprint speeds.

[5] Leiocephalus personatus is endemic to Hispaniola, but within its limited range it is a common species and no particular threats have been identified.