Like its predecessor, Leisure Suit Larry in the Land of the Lounge Lizards, it was developed for multiple platforms, including MS-DOS, Atari ST and Amiga.

Realizing that his affair with Eve was merely a one-night stand, a distraught Larry wanders off, winning the Lottery as well as a free vacation after stumbling into a dating game show.

During his preparations for the cruise ship, a microfilm falls into Larry's hands by mistake; this attracts the attention of the KGB, as well as the mad scientist Dr. Nonookee (a pun on "no nookie"), who both want to recover the film.

In order to marry Kalalau, Larry infiltrates the volcano and accidentally causes the death of Dr. Nonookee, liberating the native women he had hypnotized as slaves, including "Polyester Patti".

In the final cutscene, Larry marries the chief's daughter, the witch doctor rejuvenates him, and he makes love to Kalalau as the volcano explodes.

In addition to sharing the SCI0 engine, the game parallels the King's Quest series in its realistic art style—particularly in regard to Larry's character portrait[1]—and grand-adventure elements, including a number of diverse settings (a cruise ship, tropical islands, etc.).

[2] According to series creator Al Lowe, this lack of Leisure Suit Larry's trademark humor is an oft-cited criticism of the game.

The total sales of the first five Leisure Suit Larry games had surpassed 2 million copies by the time of Love for Sail's launch.

[5] Leisure Suit Larry Goes Looking for Love (in Several Wrong Places) received mostly highly positive reviews upon its release, including the overall scores of 9/10 from Commodore User and 90% from Computer & Video Games.

The editors wrote, "The three Larry games so far plumb new depths in computer entertainment — they're crude, suggestive, full of innuendo and double entendres and designed to appeal to the worst aspects of human nature — you'll love 'em.