Lelio Brancaccio (around 1560–1637), Marquess of Montesilvano, was a Neapolitan commander of Habsburg armies in Italy, the Low Countries and Catalonia.

Apart from a brief stint as sergeant major of a regiment of Italian infantry in the Long Turkish War, he served the Habsburgs for the rest of his life.

Taking ship from Flanders for Spain to convoy Spanish infantry, he was captured en route by an English naval squadron.

After the signing of the Twelve Years' Truce between the Habsburgs and the Dutch Republic, he returned to Naples and became a member of the Collateral Council.

In 1623, in recognition of his services to the Spanish monarchy, Philip IV of Spain created him Marquess of Montesilvano.