The series was renewed by ABC Family for a second season of fifteen episodes, which began airing on May 30, 2012, and ended on August 29, 2012.

[2] During the second season, Melissa & Joey ranked as cable television's #1 telecast at 8 o'clock across target audiences 18–34, 18–49 and 12–34 demographics.

[11][12][13] Looking to marginalize these declines, the show accelerated the availability of its episodes to non-provider-authenticated ABC Family subscribers with Hulu Plus to three weeks post broadcast.

When a family scandal leaves her niece, Lennox, and nephew, Ryder, without their parents, Mel takes them in.

Meanwhile, Joe is a former commodities trader left bankrupt after a Ponzi scheme, and finds himself searching for a job.

The show stars two former teen idols who were notable for roles they played in popular 1990s sitcoms, Lawrence for Blossom and Hart for Sabrina, the Teenage Witch.

The series marks the second time Hart and Lawrence have co-starred together in an ABC Family production; their first was the 2009 television film, My Fake Fiance.

Melissa & Joey was criticized early on for lacking sufficient chemistry between the leads and a "will they, won't they" theme present in their earlier project, My Fake Fiance.

[38] Special features include a sneak peek of the remaining season 1 episodes, bloopers, and featurettes with Melissa Joan Hart and Joey Lawrence.

[3][4] The following is a table with the average estimated number of viewers per episode, each season of Melissa & Joey on ABC Family.