[2] The name is derived from the former Kingdom of León in Spain, though it is pronounced like the American first name, "LEE-un".

The town is on the western border of the county, northwest of the city of Salamanca.

795 and Leon United Methodist Church are listed on the National Register of Historic Places.

[3][4] Leon's post office, ZIP Code 14751, opened June 20, 1837.

U.S. Route 62 is a major north-south highway through the western part of the town.

The west boundary is shared by the town of Cherry Creek in Chautauqua County.

The racial makeup of the town was 99.13% White, 0.07% Native American, 0.14% Asian, and 0.65% from two or more races.