[1] Guthrie completed his medical studies at St Bartholomew's Hospital in 1886 and subsequently sat the diplomas of both the Royal College of Surgeons and the Society of Apothecaries.
[3] Guthrie's major work was Functional Nervous Disorders of Childhood (1907), and he added chapters to Clifford Allbutt's, A System of Medicine (1896–1899; 1905–1911), and to the Diseases of Children (1913), edited by Archibald Edward Garrod, Frederick Eustace Batten and James Hugh Thursfield.
He contributed articles to the Dictionary of National Biography 1912 supplement on the physicians Charles Edward Beevor and George Alfred Carpenter.
He did not dispute the conventional view that Napoleon died from stomach cancer, and probably had hepatitis too, but argued that his post-mortem remains also showed evidence of hypopituitarism (dystrophia adiposo-genitalis) such as genital atrophy, sexual alopecia, and skeletal and tissue changes that gave a feminine appearance.
He left at 5.30 pm to travel home by Tube but, walking too close to the platform edge, he was killed when he was hit by a train as it entered the station.