It is during the heyday of Roman rule when it blooms Lepe settlement located in a small village, linked to farming their fields and fishing port of El Terron.

Based on classical texts, several authors have identified the current location of Lepe settlements with Laipe Megala (Rodrigo Caro, 1634), Laepa (García y Bellido, 1947; G. Bonsor, JP and E. Garrido Orta, 1922) and Praesidium (Luzon, 1975).

It is after the second wave of Arab conquests when Lepe becomes the economic center of the area, growing from a small farmhouse to a "city about the Ocean Sea," as was described by the geographer Yaqut al-Hamawi later in the 1229.

In the late 16th century, Marcos Alonso de la Garza left Lepe and settled in what is today the Mexican state of Durango, beginning a line of descendants, including Cpt.

Built under Philip II of Spain is the Torre del Catalán, a 16th-century lookout tower, used to warn of an impending invasion by Berber pirates.