The Leprozengracht was a canal in Amsterdam that defined one side of the Vlooienburg island.

[1] In the late 16th century it was decided to expand the old city of Amsterdam by creating a new island in this area.

[4] Vlooienburg was raised up during the second expansion of Amsterdam between 1592 and 1596 as a place to store wood, and blocks of houses were soon added.

[5] In the 1870s the houses along the canal were occupied by, among others, a furniture maker, teacher of religion, insurance broker, kosher cafe-restaurant, corn cutter and tailor.

[6] Between 1837 and 1841 a church was built opposite the end of the canal dedicated to Saint Anthony of Padua, designed by Tilman-François Suys.