While in the Airforce, Lowe trained to be a pilot on the CT114 Tutor Jet and eventually he become an Aerospace Engineering Officer at National Defense Headquarters in Ottawa where he worked with scientists who were focused on research and development projects to create airborne equipment that could be used to track Soviet nuclear submarines.

[2][6][7][8] In one half of the Halifax Project, 174 scientists from 26 countries were recruited to assess the potential role of low-dose chemical mixtures on the Hallmarks of Cancer.

The taskforce concluded that low-dose exposures to disruptive chemicals that are not individually carcinogenic may be capable of instigating and/or enabling carcinogenesis.

Lowe noted that attempts to treat this sort of relapse often involves simple combinations of chemotherapy that cannot reach enough molecular targets so many refractory cancers are unstoppable.

The researchers then tried to identify friendlier chemicals, many of which come from plants and foods that could be combined to reach many targets (key anticancer receptors, pathways, and mechanisms) with little to no toxicity at therapeutic doses.

The interdisciplinary teams reviewed each hallmark area and nominated a wide range of high-priority targets (74 in total) that could be modified to improve patient outcomes.

Neuroscience and Biobehavioral Reviews agreed to create a special issue for the project, guest editors were used, and so far, 12 open access articles have been published by the 12 teams.