[1] After graduating, she trained as a taxonomist at the Institute of Food Research, Reading where she studied Gram-positive anaerobes that had been isolated from veterinary and clinical sources.
[2] After her PhD Hoyles was awarded an IRCSET research fellowship, and joined Douwe van Sinderen's phage laboratory at University College Cork to work on gut-associated bacteriophages.
She returned to the UK on a Medical Research Council advanced scholarship to undertake a master's degree in bioinformatics and theoretical systems biology at Imperial College London.
After completing her master's degree at Imperial College London, Hoyles worked on translational systems biology as a postdoctoral research associate[4] and started to investigate host–microbiome interactions.
[7] Hoyles and McArthur identified that TMAO, a molecule found in fish and seafood, may play a role in improving cognitive function by strengthening the blood–brain barrier.