Lester Hayden Humphrey (January 22, 1850 – March 17, 1902) was an American manufacturer, banker and politician.

He engaged in the tanning and leather trade until 1872, and was Vice President of the Wyoming County National Bank from 1873-1888.

In 1890, he sold out his interest in the Hutchinson plant and succeeded his uncle Wolcott J. Humphrey as President of the Wyoming County National Bank.

Humphrey was a delegate to the 1888 Republican National Convention, and a member of the New York State Senate (46th District) from 1896 until his death in 1902, sitting in the 119th, 120th, 121st, 122nd, 123rd, 124th and 125th New York State Legislatures.

[5] On May 18, 1875, Humphrey married Maude Wilton Skinner, daughter of Illinois Supreme Court Justice Onias C.