"Let's Shake Hands" is the debut 7" single of Detroit-based American garage rock band The White Stripes.

"Let's Shake Hands" was the first song the band recorded in their living room for Dave Buick, who offered to finance the release of their first single.

[1] The style surprised Buick based on the band's live performances, but—according to an interview with The New Yorker—Jack said it was "a declaration that the White Stripes weren’t going to observe punk proprieties.

The single is backed with a cover of "Look Me Over Closely," a song written for Marlene Dietrich by folk musician Terry Gilkyson.

Highly coveted among diehard fans, this 7" remains one of the rarest and priciest items in The White Stripes' entire discography.