[1] The genus was circumscribed by German lichenologist Klaus Kalb in 2015, with Leucodermia leucomelos assigned as the type species.

Leucodermia includes lichens that were previously classified in genus Anaptychia section Polyblastidium series leucomelaenae.

[3] Characteristics of genus Leucodermia include a thallus that is either leafy (foliose) to somewhat bushy (subfruticose) with lobes that are linear-elongate, ribbon-like, and dichotomously branched.

The thallus is loosely attached to the substrate and lacks a lower cortex.

The apothecia often have pruinose discs and Polyblastidium-type ascospores, with sporoblastidia (small chambers in a thick-walled spore).