2WFD51520107045ENSG00000133706ENSMUSG00000024493Q9P2J5Q8BMJ2NM_020117NM_001317964NM_001317965NM_016460NM_134137NP_001304893NP_001304894NP_057544NP_064502NP_598898Leucyl-tRNA synthetase, cytoplasmic is an enzyme that in humans is encoded by the LARS gene.

The encoded enzyme catalyzes the ATP-dependent ligation of L-leucine to tRNA(Leu).

It is found in the cytoplasm as part of a multisynthetase complex and interacts with the arginyl-tRNA synthetase through its C-terminal domain.

Alternatively spliced transcript variants of this gene have been found; however, their full-length nature is not known.

[7] This article on a gene on human chromosome 5 is a stub.