Lexington High School's campus consists of a central quadrangle (Quad), four main academic buildings (Arts & Humanities, World Language, Mathematics, Science), a field house, and a pair of modular classrooms (mods).

[9] As of November 2023 there are ongoing plans to build a new school, with Dore+Whittier having been selected as the Owner's Project Manager, and SMMA as the architect.

[17][18] Lexington High School has a debate program consisting of three divisions: Lincoln–Douglas, Policy, and Public Forum, all taught as elective courses.

As of 2019, Lexington's debate team has won both the Policy division and the Sweepstakes Award at the State Championship for the last 45 years.

[23] Lexington has won top speakers awards at the NDCA in Lincoln-Douglas (2012) and Public Forum (2017), and at the TOC in Policy (1986, 1995).

In the National Science Bowl, LHS has placed first five times, tying with Mira Loma High School for the most first-place finishes.

[31][32] Lexington High competes within division 1 of Massachusetts Interscholastic Athletic Association’s 4th district as a member the Middlesex League.

The paper's First Amendment rights were maintained with the victory in Yeo v Town of Lexington, a case argued in the United States Court of Appeals for the First Circuit.