libRoadRunner is a C/C++ software library that supports simulation of SBML based models..[1] It uses LLVM to generate extremely high-performance code and is the fastest SBML-based simulator currently available.
[2] Its main purpose is for use as a reusable library that can be hosted by other applications, particularly on large compute clusters for doing parameter optimization where performance is critical.
[3] libroadrunner is often paired with Tellurium,[4] which adds additional functionality such as Antimony[5] scripting.
libroadrunner has been widely used in the systems biology community for doing research in systems biology modeling, as well as being a host for other simulation platforms.
The following lists a small number of those studies: A number of reviews and commentaries have been written that discuss libroadrunner: Development of libroadrunner is primarily funded through research grants from the National Institutes of Health[30]